Clean the NUC inside and out. You might need to blow a dirty unit off outside to avoid getting the lab bench dirty.
Vacuum or blow off exterior of device, focusing on ports and vents
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Remove bottom of NUC and vacuum or blow out dust
Remove RAM, storage devices, and wifi card (if any)
Use dust removing gel to clean
interior of NUC
cover
RAM chips
storage devices
Use blower or canned air to blow out the CPU fan
Remove motherboard and clean the top of the board and inside the top cover
Clean the CPU fan